The Kick Inside

Now, I’m 21 and not planning on getting pregnant anytime soon. Yet, since the day I began treatment, doctors have been protecting my phantom baby. A typical exchange in my psychiatric appointments follows this general structure:

Me, in a whiny voice: “I don’t want to take my Lith-iiiieee-ummmmmm, it makes me feel sick and I have put on tons of weight”. *sad face*


Doctor, in stern, teacherish voice: “If you don’t take your Lithium with your antidepressants then you will have to go to hospital again. And this time for much longer. Months. You will go sky high again”.

Sullen me: “I have already gone sky high even as I was taking Lithium”.

Doctor, exasperated: “Look, Lithium is the safest mood stabiliser for women of your age“.

By “my age” he means of “childbearing age”. Yet apparently Lithium should be avoided during pregnancy as it cause prenatal defects. Which begs the question- just how dangerous are other mood stabilisers to the unborn child?

The Valproate Family

Well, sodium valproate also carries a risk of foetal defects. Read the whole article on valproates, but this in particular is quite sobering:

Of 403 pregnancies in women taking antiepileptic drugs (AEDs), 87.8% resulted in a healthy live birth and 5.2% resulted in a live birth of a child with fetal malformations, ranging from neurologic to genitourinary to skeletal abnormalities. The remaining pregnancies ended in spontaneous abortion or premature death in utero.

The fetal malformation rate was significantly greater in pregnancies exposed to valproate in the first trimester, compared with those exposed to all other AEDs in the first trimester. (16.1% vs. 2.4%). Additionally, the incidence of fetal malformations was significantly higher in women taking valproate than in those taking no AEDs (16.1% vs. 3.1%).

The higher the dosage, the greater the risk according to Diana Mahoney. Reading around, statistics quoted are much the same.

Valproates and Lithium are the two most commonly prescribed true mood stabilisers used to treat Bipolar 1 in the UK.

Lamictal

Bipolar II is often treated using Lamictal. It’s also approved to treat Bipolar 1, but only when stable on other medications. As for Lamictal and pregnancy, there’s little information out there. Best I can find is this from the FDA, which says that babies born during Lamictal treatment are at higher risk of cleft palette.

So, the two “true” mood stabilisers are harmful when pregnant. Information surrounding Lamictal is shady. What can you take during pregnancy, then?


The Talk: The Doctor Will Always Discourage You Ever

Getting Pregnant

I had “The Talk” with my doctor regarding pregnancy. I have always wanted children, loving my little siblings like they were my own, in that freakish big sister way. However, I also have PCOS, meaning my periods come when the damn well want to, which reduces my chance of conceiving and heightens my chance of miscarriage.

When I told my psychiatric doctor this, he was almost relieved. “The Talk” considers the risks of pregnancy to the manic depressive woman.

I’ve been told that if I get pregnant, I can continue Lithium but need to know the risks. Problem is, Lithium is really not that effective for me. It only has a 40% success rate, and Lithium is the first line treatment for mania. So the 60% whose doctors won’t let them switch- where does that leave us?

I’ve also tried Tegretol and Zyprexa, both extremely unsuccessfully. So if I want to reduce the risk to my unborn child (note: not eliminate it), I have to continue taking the ineffective Lithium. Tegretol is also harmful to foetus’.

Another option aside from Lithium is taking an old-school antipsychotic like Haloperidol. Haloperidol is an extremely blunt tool when dealing with complicated mood episodes and carries risks such as tardive dyskinesia. See your neighbourhood schizophrenic who creeps you out because their tongue moves in their mouth like a blind worm? It’s likely they have tardive dyskinesia induced by old school antipsychotics.

Haloperidol and its cousin Thorazine are both pills I have taken and I wouldn’t trust myself on them in pregnancy.

So, that was one part of the talk.

I then got the lowdown on the risks of becoming pregnant. The National Alliance of Mental Illness articulates it pretty starkly:

Because bipolar disorder emerges during young adulthood and persists throughout the lifespan, women of childbearing age are at risk for this illness. Pregnancy and delivery can influence the symptoms of bipolar disorder: pregnant women or new mothers with bipolar disorder have a sevenfold higher risk of hospital admission and a twofold higher risk for a recurrent episode, compared with those who have not recently delivered a child or are not pregnant.

Basically- we might go absolutely nuts.


Tammy

I witnessed this first hand in hospital with a heavily pregnant bipolar woman called Tammy. Tammy was extremely violent and suffering from psychotic delusions. She believed her child was eating her from the inside and would call every day for the nurses to abort it. It was shocking to witness. She was being medicated with Haloperidol and various sedatives and would be quiet every few hours before the halls would rattle with her petrified shrieks.


Shite

Thing is, I have to listen as I know I have a history of psychotic mania and psychotic depression. So it frightens me to know that that most happy of events- carrying a baby- might make me so ill that I could hurt myself or my child.

The doctor was gentle with this information. He’s blunt like that. He wasn’t mean. He was nice but a matter of fact.

I had always feared post-natal depression but I know that in my depressions, save for the bleakest I have experienced, I can always be reached. Some anchor is dropped, some voice is faraway above the well’s mouth, but I can hear it. It’s a whisper, but I can hear it.

Psychosis is not the same. Psychosis is unreachable, unreal, uninhabitable and unimaginable for anyone other than the person locked inside it.

It horrifies me that I might become psychotic while pregnant. That all us manic depressive ladies out there might fear the thing inside them. Or adore it, too much.

If that wasn’t enough to put me off…

Manic depression is hereditary

Mental illness giveth, mental illness taketh away…

While I can see some valuable things I have gained from being a Mentally Interesting Girl diagnosed young-ish, that isn’t something I’d ever want to pass on.

I do have some insight into things I would never have even thought about otherwise. Things like psychosis, mania, depression, suicide and oh, positive things too. Like how people endure and carry on. And how they recognise- by and large- that mental illness sucks, it could be worse. Granted, I only had this sort of self-awareness very recently, but those clear times are quite valuable. My illness is now a part of me. Not the whole of me, but it’s part of my identity because it affects everything at the core of who I am- my moods, my emotions, my energy, my creative abilities.

But, that said, I would never want to pass it on. Manic depression is hereditary. And as well as giving me some insights, it’s taken me on hell-rides, severely truncated what I’m likely to achieve in life and removed a modicum of control from my moods and emotions, on who I could have been.

What we have to ask ourselves then, when we think of getting pregnant or getting someone pregnant- do we want to pass this on?


Crap Poetry Aged 15

When I was 15, I wrote a really shit poem called, “The Heirloom In my Family Is Mental Illness”. Oh woe! I hear you cry. While the rest of the poem was as teenage wankish as you could get, the title did hold truth.

Mental illness runs in my family. There is a vein coursing through us, from my great-grandmother, to her daughter, to my mother, to me. Sadly, it runs thus on the other side too, but that side bred alcoholism, which eventually stole my father from me.

Mental illness can come from nowhere and it can be caused by traumatic life events. But of all the psychiatric illnesses, bipolar disorder seems to have the strongest genetic link.


Sigh

So, I had that merry onslaught chucked at me when my pregnancy questions peeked above the parapet.

Becoming pregnant when you’re manic depressive is tough. It’s not impossible, though. Pregnancy is tough to deal with whatever the circumstances. It’s just that much harder when you suffer from a mental illness. And if we were all afraid of passing on the “faulty gene”, we wouldn’t be here, us Mentally Interesting folks, and that would be a loss.

I’m going to take the advice of Generic Wise Man and wait and see. You never know.

10 Responses

  1. Yeah, a lot of people say to me that my daughter has a 15% chance of being BiP. Well I say back – she’s got an 85% chance of NOT been.

  2. You are in a bitch of a situation. In the US (I’m from Australia) they use topiramate, my suspicion is that it is a weak mood stabiliser and it probably has similar risks of fetal malformations… but it doesn’t cause the weight gain, which might help with the PCOS. As to the hereditary mental illness thing, my feeling is that the severity of someone’s symptoms and the quality of their life depends on a lot of stuff – the father’s genes, the home environment, etc., and a however many percent chance of inheriting BPAD doesn’t mean game over.

    It’s a horrible situation. It’s a pity you can’t donate eggs or something.

  3. I had my children long before I was ever diagnosed. Therefor there were no risks due to medications. My son seems to be normal. My daughter has been living a nightmare since her early teens. I love my children and adoremy grandchildren. I would not wish them out of this world for anything. EVER. They are the joy of my life and the only pleasure I get in life. I stay alive for them. Before I was diagnosed there was no known history of any mental illness in my family, so there were no choices to be made. My grandparents were adopted on both sides so the history isnt known. If were to do it all over again knowing what I know now, knowing how my daughter would suffer………….. I dont know that I would have children. I think if I were in the position of knowing how my illness was going to manifest and how it would affect my life and my childrens, how it would be passed down and one of them would suffer, and I hadnt yet met them, so I wasnt giving them up. I think I would make the decision to remain childless. I’m not saying that is a right decision for everyone else or even for one other person. I am just saying that I have seen so very much come of it that I would have to make that decision.

  4. Plus I still have to deal with the possiblities that my grandchildren will also be going thru this nightmare. What a horrifying thought

  5. Thank you for such a fabulous yet sobering Blog… I’m 32 and I have been diagnosed Bi-Polar II for coming up 2 years. However spent 15 years on Anti Depressants before receiving the right Diagnosis. For the last 14 years I have been telling myself that I don’t want children, I don’t want to put them at risk of a. Suffering from a mental illness and b. Having a mother that suffers from a mental illness. However as my clock starts to tick ever so lightly, I feel this intense, sense of lose and confusion.

  6. Had my 2 children long before being diagnosed, and BP sister had 2 before and 2 after being diagnosed (no family history before us).
    My son has battled with suicidal depression, would never seek any treatment, but seems to have cured himself (now aged 27), my daughter (aged 19) is currently battling bulimia and obsessive regrets, and worries she might be BP if she sought a diagnosis.
    My sister’s children so far seem ok, although the youngest was taken into care and then adopted (different dad to the others) because my sister was judged unfit. Latterly the only times my sister was sane was when she was pregnant. She hung herself, aged 42. I am utterly glad I have my children and hers. They have different fears and feelings about their own experiences as children of mad mum’s, and different feelings and fears about being parents themselves. In the end, bearing and raising children is just about the greatest risk any woman can take whatever your state of mind. It can only be a personal choice (in
    a world where most of us reading this have that luxury).

  7. This is very nice and informative post. I have bookmarked your site in order to find out your post in the future.

  8. […] born without it.) I obviously did not choose to avoid having children to avoid passing it on, as some psychiatrists have infamously advocated, and the thought of a genetic test with its resultant “therapeutic” abortion for […]

  9. […] The Kick Inside My Friend, Brendan Hollywood Who Am I? All the Decembers I Have Seen […]

  10. […] The Kick Inside My Friend, Brendan Hollywood All the Decembers I Have Seen […]

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